Journal of Diabetes Research

Diabetes and Nonalcoholic Fatty Liver Disease


Publishing date
15 Dec 2011
Status
Published
Submission deadline
15 Jun 2011

1Division of Endocrinology, Diabetology, Nephrology, Vascular Disease and Clinical Chemistry, Department of Internal Medicine, University of Tübingen, Otfried-Müller Straße 10, 72076 Tübingen, Germany

2Stable Isotope Laboratory, Institute of Clinical Physiology, CNR, Via Moruzzi 1, 56100 Pisa, Italy

3Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA

4Department of Kinesiology, University of Montreal, CP 6128, Succ. Centre-Ville, Montreal, QC, Canada H3C 3J7


Diabetes and Nonalcoholic Fatty Liver Disease

Description

With a prevalence of up to 30% in the general population in industrialized countries, as well as an increasing prevalence in childhood population, nonalcoholic fatty liver disease (NAFLD) represents the most common today cause of chronic liver disease and constitutes a major risk factor for progression to liver failure, cirrhosis, and hepatocellular carcinoma. In addition, in the recent years, it emerged that NAFLD plays a critical role in human metabolism. Several studies confirmed that NAFLD is strongly associated with insulin resistance and precedes the manifestation of type 2 diabetes and cardiovascular disease. However, the responsible mechanisms involved in the process of hepatic fat accumulation and in the crosstalk of fatty liver with other tissues important for regulation of metabolism in humans are not fully understood.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the various genetic and environmental mechanisms leading to NAFLD and explaining its relationship with diabetes. Potential topics include, but are not limited to:

  • State-of-the-art methods to assess liver fat content and its effects on metabolism
  • Diagnostic procedures: sensitivity and specificity
  • Biomarkers of fatty liver and liver disease, including but not limited to markers of diabetes
  • Genetic determinants of NAFLD and its metabolic complications
  • Role of inflammation and cytokines in the pathogenesis/progression of NAFLD
  • Bile acids as regulators of hepatic fat accumulation and glucose metabolism
  • Role of NAFLD in cardiovascular disease
  • Estrogens/hormone replacement therapy in the pathogenesis of NAFLD and type 2 diabetes
  • NAFLD and diabetes in children: particular features and challenges
  • Effect of insulin-sensitizing agents on diabetes and NAFLD
  • Effectiveness of bariatric surgery on diabetes and NAFLD
  • Novel therapy and research directions

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jdr/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 404632
  • - Editorial

Diabetes and Nonalcoholic Fatty Liver Disease

Konstantinos Kantartzis | Amalia Gastaldelli | ... | Jean-Marc Lavoie
  • Special Issue
  • - Volume 2012
  • - Article ID 716404
  • - Review Article

The Role of Metformin in the Management of NAFLD

Angela Mazza | Barbara Fruci | ... | Antonino Belfiore
  • Special Issue
  • - Volume 2012
  • - Article ID 361863
  • - Research Article

Cholesterol Synthesis Is Associated with Hepatic Lipid Content and Dependent on Fructose/Glucose Intake in Healthy Humans

Guenther Silbernagel | Dieter Lütjohann | ... | Andreas Fritsche
  • Special Issue
  • - Volume 2012
  • - Article ID 789730
  • - Research Article

Inhibition of Aldose Reductase Activates Hepatic Peroxisome Proliferator-Activated Receptor-α and Ameliorates Hepatosteatosis in Diabetic db/db Mice

Longxin Qiu | Jianhui Lin | ... | James Y. Yang
  • Special Issue
  • - Volume 2012
  • - Article ID 145754
  • - Review Article

Diagnosis and Evaluation of Nonalcoholic Fatty Liver Disease

Mikako Obika | Hirofumi Noguchi
  • Special Issue
  • - Volume 2012
  • - Article ID 716425
  • - Review Article

Role of Transcription Factor Modifications in the Pathogenesis of Insulin Resistance

Mi-Young Kim | Jin-Sik Bae | ... | Yong Ho Ahn
  • Special Issue
  • - Volume 2012
  • - Article ID 351974
  • - Research Article

Predictors of Impaired Glucose Regulation in Patients with Non-Alcoholic Fatty Liver Disease

Erifili Hatziagelaki | Drosos E. Karageorgopoulos | ... | George Dimitriadis
Journal of Diabetes Research
 Journal metrics
Acceptance rate32%
Submission to final decision68 days
Acceptance to publication26 days
CiteScore5.500
Impact Factor2.965
 Submit

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.