Research Article
Development of AIDA v4.3b Diabetes Simulator: Technical Upgrade to Support Incorporation of Lispro, Aspart, and Glargine Insulin Analogues
Table 3
Parameter set derived from Trajanoski et al. [
35].
| | Parameter | Value | Description |
| | Q/mL2 IU−2 | 76 | Chemical equilibrium constant | | Bd/min−1 | 1.18*10−2 | Absorption rate constant for dimeric insulin | | Bm/min−1 | 1.22*10−2 | Absorption rate constant for monomeric insulin | | P/min−1 | 0.5 | Rate constant | | D/cm² min−1 | 8.4*10−5 | Diffusion constant for soluble insulin | | Dm/cm² min−1 | 1.66*10−4 | Diffusion constant for monomeric insulin analogues | | KS/min−1 | 0.09 | Plasma insulin elimination rate | | Vp/l | 12 | Volume of plasma insulin compartment | | KS/min−1 | 55 | Plasma insulin elimination rate constant for monomeric insulin analogues |
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