Journal of Environmental and Public Health / 2016 / Article / Tab 4

Research Article

Cross-Sectional Study of Polybrominated Flame Retardants and Self-Reported Attention Deficit Hyperactivity Disorder in US Youth Aged 12–15 (NHANES 2003-2004)

Table 4

Crude and adjusted odds ratio (OR) for ADHD diagnosed by a health care provider and PBDE exposure.

ADHD
Yes
ADHD
No
Weighted crude odds
(95% CI)
valueUnweighted crude odds
(95% CI)
valueWeighted adjusted odds
(95% CI)
valueUnweighted adjusted odds
(95% CI)
values

BDE-28
 Lipid-adjusted 242821.01 (0.51, 1.99)0.981.11 (0.63, 1.94)0.721.16 (0.51, 2.67)0.680.97 (0.52, 1.82)0.93
 Wet weight242820.93 (0.42, 2.08)0.840.90 (0.51, 1.57)0.700.97 (0.38, 2.45)0.940.85 (0.50, 1.78)0.86

BDE-47
 Lipid-adjusted 252840.83 (0.48, 1.44)0.520.99 (0.64, 1.54)0.971.36 (0.72, 2.56)0.321.03 (0.63, 1.67)0.91
 Wet weight252841.17 (0.68, 2.05)0.541.01 (0.65, 1.57)0.961.22 (0.62, 2.40)0.551.01 (0.62, 1.66)0.96

BDE-99
 Lipid-adjusted 242790.82 (0.44, 1.52)0.500.97 (0.61, 1.46)0.801.51 (0.70, 3.25)0.261.06 (0.65, 1.71)0.82
 Wet weight242791.25 (0.65, 2.42)0.471.06 (0.69, 1.63)0.791.37 (0.63, 2.98)0.391.04 (0.64, 1.69)0.87

BDE-100
 Lipid-adjusted 252880.72 (0.36, 1.44)0.320.95 (0.61, 1.48)0.831.53 (0.73, 3.23)0.241.04 (0.64, 1.69)0.84
 Wet weight252881.36 (0.70, 2.64)0.341.05 (0.68, 1.63)0.821.37 (0.66, 2.82)0.371.03 (0.64, 1.67)0.91

BDE-153
 Lipid-adjusted 252881.27 (0.56, 2.90)0.541.02 (0.66, 1.57)0.931.43 (0.57, 3.56)0.421.02 (0.61, 1.65)0.95
 Wet weight252881.29 (0.52, 3.21)0.560.98 (0.64, 1.51)0.930.27 (0.56, 2.90)0.541.00 (0.60, 1.67)0.99

Sum PBDEs
 Lipid-adjusted 242781.24 (0.63,2.42)0.500.99 (0.62, 1.58)0.971.41 (0.70, 2.83)0.310.99 (0.60, 1.64)0.97
 Wet weight242781.19 (0.63, 2.25)0.561.00 (0.63, 1.59)0.991.24 (0.62, 2.50)0.520.99 (0.58, 1.68)0.96

Sum PBDEs
 Lipid-adjusted below 75%11139RefRefRefRefRefRefRefRef
 Above 75% 131390.87 (0.19, 3.91)0.840.76 (0.31, 1.84)0.540.59 (0.10, 3.56)0.530.70 (0.38, 1.29)0.26
 Wet weight
  Below 75%16205RefRefRefRefRefRef
  ≥75%8731.03 (0.19, 5.65)0.970.72 (0.29, 1.75)0.470.90 (0.21, 3.72)0.870.60 (0.22, 1.64)0.32

Sum PBDE
 Lipid-adjusted 1st tertile (lowest)11131RefRefRefRefRefRefRefRef
 2nd tertile5785.75 (2.02, 16.34)0.0031.31 (0.44, 3.92)0.636.16 (1.19, 31.90)0.031.34 (0.39, 4.64)0.64
 3rd tertile (highest) 8691.09 (0.23, 5.22) 1.64 (0.56, 4.80)0.910.73 (0.28, 1.90)0.520.99 (0.23, 4.29)0.990.66 (0.23, 1.94)0.45
 Wet weight
  1st tertile (lowest)10133RefRefRefRefRef
  2nd tertile5771.55 (0.39, 6.28)0.511.23 (0.33, 4.63)0.761.81 (0.41, 8.04)0.411.17 (0.33, 4.16)0.81
  3rd tertile (highest) 9681.96 (0.66, 5.81)0.211.17 (0.37, 3.76)0.790.63 (0.17, 2.36)0.460.47 (0.16, 1.38)0.17

Natural log transformed.
Weighted analysis was conducted using NHANES sampling weights to account for the complex sampling design. According to NHANES guidelines, the sample weights were used which corresponded to subsample that had their serum analyzed for PBDEs [15].
Adjusted for lead, sex, birthweight, BMI, daycare attendance, and prenatal smoke exposure.

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