Research Article

The LINA Study: Higher Sensitivity of Infant Compared to Maternal Eosinophil/Basophil Progenitors to Indoor Chemical Exposures

Table 5

Correlation of indoor volatile organic compound (VOC) concentrations and IL-3-, IL-5-, or GM-CSF-stimulated eosinophil/basophil (Eo/B) colony forming units (CFUs) in peripheral blood of two-year-old children and their mothers. Shown are aromatic VOCs as well as the sum of all analysed VOCs. Data are presented as Spearman’s rank correlations; values < 0.05 are considered to be significant and printed in bold.

VOCsEo/B CFUs motherEo/B CFUs child
IL-3IL-5GM-CSFIL-3IL-5GM-CSF

Benzene0.0290.2750.0760.2990.5440.2060.1010.2020.0360.2580.0360.281
Toluene0.8990.0160.8340.0360.7790.0960.7500.0400.3140.1260.4330.107
m + p-Xylene0.8720.0210.9570.0090.4470.2560.4180.1010.0060.3320.0170.318
o-Xylene0.4830.0900.882−0.0260.4720.2430.1740.1680.0050.3450.0020.407
Styrene0.7770.0370.282−0.1840.7280.1190.8300.0270.5070.0830.8070.033

Sum of all VOCs0.0930.2130.8480.0330.1480.4670.0450.2460.0130.3030.0470.267