Research Article

Diagnostic Errors in Tuberculous Patients: A Multicenter Study from a Developing Country

Table 1

Characteristics of patients and their tubercular diseases.

Number of TB patients158

Age (mean ± SD)52.4 ± 21.1 (15–59)
Male to female ratio1.26
Site of involvement
 Pulmonary TB
  Smear positive96 (59.6%)
  Smear negative4 (2.5%)
 Extrapulmonary TB
  Pleural15 (9.3%)
  CNS13 (8.1%)
  Disseminated16 (9.9%)
  Bone and joint6 (3.7%)
  Lymph nodes4 (2.5%)
  Peritoneal cavity3 (1.9%)
  Other sites4 (2.5%)
Nationality
 Iranian151 (94.9%)
 Afghan7 (4.4%)
Educational level
 Illiterate61 (39.1%)
 Secondary school or lower59 (37.8%)
 High school diploma or associate degree31 (19.9%)
 Academic5 (3.2%)
Geographical strata
 Urban133 (84.2%)
 Rural25 (15.8%)
History of close contact with TB38 (24%)
Previous history of TB16 (10.2%)
Drug addiction33 (20.8%)
History of recent imprisonment11 (6.9%)
Underlying conditions
 Diabetes mellitus40 (25.3%)
 Hypertension and heart disease26 (16.4%)
 Chronic pulmonary disease13 (13.2%)
 Taking corticosteroids or other immunosuppressive drugs11 (6.9%)
 HIV/AIDS9 (5.6%)
Overall rate of diagnostic errors154 (97.5%)
 One type of error26 (16.8%)
 Two types of error21 (13.6%)
 Three or more types of error107 (69.4%)
Life-threatening complications from admission to discharge
 TB-associated sepsis or acute respiratory failure29 (18.5%)
 Massive hemoptysis13 (8.3%)
 Major thromboembolic events11 (7.6%)
 Pneumothorax/pyopneumothorax2 (1.2%)
 Progressive pneumothorax requiring surgical shunting2 (1.2%)
 Others13 (7.6%)