Journal of Environmental and Public Health / 2022 / Article / Tab 1 / Review Article
[Retracted] Correlation Analysis of Inflammatory Markers CRP and IL-6 and Postoperative Delirium (POD) in Elderly Patients: A Meta-Analysis of Observational Studies Table 1 Basic characteristics, grouping characteristics, and influencing indicators of included literatures.
Author and publication date Study design Patients number Mean age (year) Surgery type Case/control PODs Inflammatory markers Blood sample collect point (after operation) Xiang et al. [9 ] Prospective cohort study 160 70.1 Laparoscopic surgery for colon carcinoma 39/121 CRP Day 1 Chen et al. [10 ] Prospective cohort study 266 62 ± 8.3 Coronary artery bypass graft 85/181 IL-6 18 h Li et al. [14 ] Prospective cohort study 37 60 Total hip-replacement surgery 17/20 IL-6, S-100b, TNF-α 1 h Brattinga et al. [15 ] Prospective cohort study 311 72 (range 65-89) Oncologic surgery 38/273 CRP, IL-1β , IL-6, IL10 1 h Lv et al. [16 ] Prospective cohort study 221 Acute type A aortic dissection patients treated with open surgical repair 31/190 IL-6 24 h Cereghetti et al. [17 ] Prospective cohort study 618 67 (range 59-74) Cardiac surgery 244/374 CRP 24 h Plaschke et al. [18 ] Prospective cohort study 114 Open-heart cardiac surgery 34/80 IL-6 1 h Neerland et al. [19 ] Prospective cohort study 60 84 Hip fracture surgery 46/14 CRP, IL-6 24 h van Munster et al. [20 ] Prospective cohort study 98 Hip fracture surgery 50/48 IL-6 24 h Plas et al. [21 ] Prospective cohort study 136 60 (range 50-76) Cytoreductive surgery 38/98 CRP 24 h Khan et al. [22 ] Prospective cohort study 71 62.6 (range 52.9-69.3) Esophagectomy 26/45 CRP 24 h Ren et al. [23 ] Prospective cohort study 206 Cervical or lumbar surgery 12/194 CRP Within 2 days Pol et al. [24 ] Prospective cohort study 277 Vascular surgery 16/261 CRP Within 5 days Slor et al. [25 ] Prospective cohort study 121 Hip fracture surgery 41/80 CRP Day1~day5 Hasegawa et al. [26 ] Retrospective cohort study 188 Oral cancer surgery 29/159 CRP Day 3 Pan et al. [27 ] Prospective cohort study 83 Lumbar spine surgery 12/71 CRP 24 h
Abbreviations: POD: postoperative delirium; IL-6: interleukin-6; CRP: C-reactive protein; TNF-α : tumor necrosis factor-α .