[Retracted] Correlation Analysis of Inflammatory Markers CRP and IL-6 and Postoperative Delirium (POD) in Elderly Patients: A Meta-Analysis of Observational Studies

Table 1

Basic characteristics, grouping characteristics, and influencing indicators of included literatures.

Author and publication date	Study design	Patients number	Mean age (year)	Surgery type	Case/control PODs	Inflammatory markers	Blood sample collect point (after operation)
Xiang et al. [9]	Prospective cohort study	160	70.1	Laparoscopic surgery for colon carcinoma	39/121	CRP	Day 1
Chen et al. [10]	Prospective cohort study	266	62 ± 8.3	Coronary artery bypass graft	85/181	IL-6	18 h
Li et al. [14]	Prospective cohort study	37	60	Total hip-replacement surgery	17/20	IL-6, S-100b, TNF-α	1 h
Brattinga et al. [15]	Prospective cohort study	311	72 (range 65-89)	Oncologic surgery	38/273	CRP, IL-1β, IL-6, IL10	1 h
Lv et al. [16]	Prospective cohort study	221		Acute type A aortic dissection patients treated with open surgical repair	31/190	IL-6	24 h
Cereghetti et al. [17]	Prospective cohort study	618	67 (range 59-74)	Cardiac surgery	244/374	CRP	24 h
Plaschke et al. [18]	Prospective cohort study	114		Open-heart cardiac surgery	34/80	IL-6	1 h
Neerland et al. [19]	Prospective cohort study	60	84	Hip fracture surgery	46/14	CRP, IL-6	24 h
van Munster et al. [20]	Prospective cohort study	98		Hip fracture surgery	50/48	IL-6	24 h
Plas et al. [21]	Prospective cohort study	136	60 (range 50-76)	Cytoreductive surgery	38/98	CRP	24 h
Khan et al. [22]	Prospective cohort study	71	62.6 (range 52.9-69.3)	Esophagectomy	26/45	CRP	24 h
Ren et al. [23]	Prospective cohort study	206		Cervical or lumbar surgery	12/194	CRP	Within 2 days
Pol et al. [24]	Prospective cohort study	277		Vascular surgery	16/261	CRP	Within 5 days
Slor et al. [25]	Prospective cohort study	121		Hip fracture surgery	41/80	CRP	Day1~day5
Hasegawa et al. [26]	Retrospective cohort study	188		Oral cancer surgery	29/159	CRP	Day 3
Pan et al. [27]	Prospective cohort study	83		Lumbar spine; surgery	12/71	CRP	24 h

Abbreviations: POD: postoperative delirium; IL-6: interleukin-6; CRP: C-reactive protein; TNF-α: tumor necrosis factor-α.