[Retracted] MicroRNA-340 and MicroRNA-450b-5p: Plasma Biomarkers for Detection of Non-Small-Cell Lung Cancer
Table 2
Correlation of plasma levels of miR-340 and miR-450b-5p with clinical and pathological characteristics of NSCLC patients.
Plasma miR-340
Plasma miR-450b-5p
Age
≤60
28
>60
92
0.731
0.915
Gender
Female
28
Male
92
0.567
0.233
Histotype
Squamous cell carcinoma
36
Adenocarcinoma
84
0.852
0.906
Adjuvant chemotherapy
No
84
Yes
36
0.293
0.053
Radiotherapy
No
112
Yes
8
0.079
0.087
Smoke habits
Never smoker
9
Former smoker
59
0.626 ± 0.269
1.330 ± 0.450
Smoker
52
0.648 ± 0.277
1.371 ± 0.437
P
0.895
0.673
T stage
T1
43
T2
60
T3
17
P
< 0.001
< 0.001
N stage
N0
82
N1
27
N2
11
< 0.001
< 0.001
TNM stage
Stage I (A + B)
50
Stage II (A + B)
59
Stage III A
11
< 0.001
< 0.001
Tumor grade
G1
15
G2
73
G3
32
0.027
0.104
Note: Smokers (smoking history: at least 5 years, smoking exposure: about more than 20 packs/year); never-smokers (subjects with no history of past and present smoking, neither active nor passive); former smokers (those who have quit smoking).