Green Coffee Bean Extract Potentially Ameliorates Liver Injury due to HFD/STZ-Induced Diabetes in Rats

Figure 6

Effect of green coffee water extract (50 and 100 mg kg⁻¹) or metformin (200 mg kg⁻¹) on mRNA expression of lipogenesis-related genes following high-fat diet-streptozotocin-induced diabetes in male rats. mRNA expression data are recorded as the mean ± SE of three assays in duplicate referenced to GAPDH and represented as fold changes (log2 scale) as compared with the mRNA levels of the control group. ^aRepresents the statistical significance relative to that of the CNTR group at  < 0.05. ^bRepresents the statistical significance relative to that of the HDF/STZ group at  < 0.05. ^cRepresents the statistical significance relative to that of the HDF/STZ-Met group at  < 0.05. ^dRepresents the statistical significance relative to that of the HDF/STZ-GCBE (50 mg kg⁻¹) group. ^eRepresents the statistical significance relative to that of a group HDF/STZ-GCBE (100 mg kg⁻¹) group.