Protective Effects of Aqueous Extracts of the Herb of Paederia scandens (Lour.) Merr. against HCl/EtOH-Induced Gastric Ulcer in Rats: Involvement and Inhibitors’ Identification of NF-κB Signaling

Table 2

The details of ten hypotheses generated by HipHop.

Hypo	Features	Rank	Direct hit	Partial hit	Max fit
1	HDDA	74.808	111111	000000	4
2	HDDA	74.808	111111	000000	4
3	HDDA	74.289	111111	000000	4
4	HDDA	74.289	111111	000000	4
5	HDDA	74.289	111111	000000	4
6	HDAA	73.679	111111	000000	4
7	HDAA	73.679	111111	000000	4
8	HDAA	73.679	111111	000000	4
9	HDDA	73.476	111111	000000	4
10	HDDA	73.476	111111	000000	4

Note: Each row represents a pharmacophore model. The meaning of each column is as follows (using 01 as an example). Features: HDDA, this pharmacophore contains 1 hydrophobic feature, 2 hydrogen bond donors, and 1 hydrogen bonding acceptor feature. Rank: 74.808, the scoring value for this pharmacophore model is 74.808. Direct hit: 111111, the potency profile of this pharmacophore model is matched to all 6 small molecules. Partial hit: 000000, this pharmacophore model matches the 6 small molecule fractions with a number of potency profiles of 0. Max fit: 4, maximum match value is 4, i.e., all 4 potency characteristics can be matched.