The Polysaccharide from Dendrobium officinale Can Improve Mice with Sjögren’s Syndrome by Regulating BAFF and Fas Expressions

Figure 6

DOP downregulates Fas/Fas-L mRNA and protein expression in the SMG of ESS mice. (a, b) qRT-PCR to detect Fas and Fas-L expressions in SMG. (c, d) The mean optical density values of Fas and Fas-L protein expressions in SMG of each group of mice. Immunohistochemical methods to detect the Fas (e) and Fas-L (f) protein expression changes in the SMG of each group of mice. The top panel displays the image under 4x objective, while the bottom panel showcases the image under 20x objective in the black rectangular box in the upper panel. A value of was considered statistically significant. , , , and vs. mice in the model group.