Aqueous Extract of Sparganii Rhizoma and Curcumae Rhizoma Induces Apoptosis and Inhibits Migration in Human Oral Squamous Cell Carcinoma

Figure 7

Schematic diagram summarize mechanism by which ROS production and ER stress-regulated apoptosis are induced in human OSCC. SRCR induced apoptotic signaling in OSCC cells by triggering ROS accumulation, ER stress, mitochondrial dysfunction, and caspase activation.