Network Pharmacology-Based Approach to Explore the Total Flavonoids of Phellinus igniarius against Hyperuricemia via Regulating the Nrf2/HO-1-ROS-ER Signaling Pathway

Figure 7

Effect of TFPI on ROS-induced apoptosis in HK-2 cells. (a) Light microscope observation of cell morphology. (b) Fluorescence-inverted microscope observation of cell nuclear morphology. The arrows are to indicate the morphology of nuclear fragmentation. (c) Effect of TFPI on the LDH release rate of HK-2 cells. (d) Flow cytometry was used to detect HK-2 cell apoptosis. Data are means ± SD (n = 3).  < 0.01, compared with the control; ^# < 0.05, ^## < 0.01, compared with the model.

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