Ursolic Acid Inhibited Cholesterol Esterase and Pancreatic Lipase Activities and Decreased Micellar Cholesterol Solubility In Vitro

Figure 5

ITC for UA binding to CEase (a) and PL (b) at 298 K: (upper) raw data plot of titration heat flow with time (sec); (below) total heat released by titration with UA concentration. The black line indicates the least squares regression best-fit line. The histogram shows the changes in the thermodynamic parameters.

(a)

(b)