Allicin-Mediated Cell Cycle Regulation Reverses Taxol Resistance in NSCLC: Molecular Insights and Therapeutic Potentia

Figure 5

The effect of allicin combined with Taxol on cell cycle arrest in A549/Taxol cells (a) Analysis of cell cycle distribution of A549/Taxol after 24 h treatment with allicin and Taxol by flow cytometry; (b) the expression level of cell cycle related proteins was detected by western blot. The results of relative protein expression were expressed by histogram. Single factor analysis of variance (ANOVA) was used for statistical comparison, and then Dunnett’s posttest was used for multiple comparisons (n = 3). The data were expressed as mean ± SD, compared with the control group,  < 0.05,  < 0.01,  < 0.001.

(a)

(b)

(c)

(d)