Interaction and Binding Kinetics of Different Substituted Pyrazines with HSA: Based on Multispectral, Physiological Activity, and Molecular Dynamics Simulations

Figure 4

UV-vis absorption spectra of HSA in the presence of different pyrazines: (a) 2,3-DMTP, (b) 2,5-DMTP, (c) TMTP, and (d) TTMP,  = 1.25 × 10⁻⁵ mol·L⁻¹, T = 301 K, and (A–F): 0, 0.75, 1.5, 2.25, 3.0, 3.75 (×10⁻⁵ mol·L⁻¹).

(a)

(b)

(c)

(d)