Salidroside Alleviates Myocardial Ischemia Reperfusion by Balancing Mitochondrial Homeostasis via Nrf2

Figure 6

SAL ameliorated H/R-induced injury in H9c2 cells via Nrf2. (a) Molecular docking between SAL and Nrf2. (b) Cellular thermal shift assay (CETSA) was used to determine the effect of SAL on Nrf2 protein stability. (c) Cell viability of H9c2 cells treated with ML385 (5 μM). (d, e) The AST and LDH release of H9c2 cells treated with ML385 (5 μM) followed by H/R stimulation.

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