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Journal of Healthcare Engineering
Volume 1, Issue 3, Pages 461-476
Research Article

The Effect of Intraocular Pressure on the Outcome of Myopic Photorefractive Keratectomy: A Numerical Approach

Elena Lanchares,1,2,3 Begoña Calvo,1,2,3 María A. del Buey,4 José A. Cristóbal,4 and Manuel Doblaré1,2,3

1Group of Structural Mechanics and Materials Modelling (GEMM), Aragón Institute of Engineering Research (I3A), Universidad de Zaragoza, Spain
2Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain
3Aragon Health Sciences Institute, Spain
4Department of Ophthalmology, University Hospital, Universidad de Zaragoza, Spain

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Photorefractive Keratectomy (PRK) is a surgical procedure widely performed to correct myopia. In this work, the effect of the intraocular pressure (IOP) on the refractive correction achieved by the PRK surgery was analyzed using a numerical model. Simulations of PRK surgery at 10, 15 and 21 mmHg of IOP were performed and the post-surgical diopters were estimated. For low and medium values of IOP (10 and 15 mmHg), the computed results were close to those used by clinicians based on experience and defined without considering the IOP, while an undercorrection was predicted for the highest value of IOP (21 mmHg). From these results, we suggest that IOP should be considered in the determination of the depth of ablation, in addition to other factors such as the level of myopia or the corneal central thickness.