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Journal of Healthcare Engineering
Volume 3, Issue 2, Pages 279-298
Research Article

Addressing the Donor Liver Shortage with EX VIVO Machine Perfusion

Maria-Louisa Izamis,1 Tim a. Berendsen,1 Korkut Uygun,1 and Martin L. Yarmush1,2

1Center for Engineering in Medicine/Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Burns Hospital, Boston MA, USA
2Department of Biomedical Engineering, Rutgers University, Piscataway, NJ, USA

Received 1 May 2011; Accepted 1 October 2011

Copyright © 2012 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [5 citations]

The following is the list of published articles that have cited the current article.

  • Maria-Louisa Izamis, Herman Tolboom, Basak Uygun, Francois Berthiaume, Martin L. Yarmush, and Korkut Uygun, “Resuscitation of Ischemic Donor Livers with Normothermic Machine Perfusion: A Metabolic Flux Analysis of Treatment in Rats,” PLoS ONE, vol. 8, no. 7, pp. e69758, 2013. View at Publisher · View at Google Scholar
  • Bote G. Bruinsma, Tim A. Berendsen, Maria-Louisa Izamis, Martin L. Yarmush, and Korkut Uygun, “Determination and extension of the limits to static cold storage using subnormothermic machine perfusion,” International Journal of Artificial Organs, vol. 36, no. 11, pp. 775–780, 2013. View at Publisher · View at Google Scholar
  • Liu, Yarmush, Berendsen, Izamis, Uygun, and Uygun, “Perfusion defatting at subnormothermic temperatures in steatotic rat livers,” Transplantation Proceedings, vol. 45, no. 9, pp. 3209–3213, 2013. View at Publisher · View at Google Scholar
  • Sara Reardon, “Supercooled livers last for days,” Nature, 2014. View at Publisher · View at Google Scholar
  • Maria-Louisa Izamis, Sinem Perk, Candice Calhoun, Korkut Uygun, Martin L. Yarmush, and François Berthiaume, “Machine perfusion enhances hepatocyte isolation yields from ischemic livers,” Cryobiology, vol. 71, no. 2, pp. 244–255, 2015. View at Publisher · View at Google Scholar