Chemothermal Therapy for Localized Heating and Ablation of Tumor

Deng, Zhong-Shan; Liu, Jing

doi:https://doi.org/10.1260/2040-2295.4.3.409

Journal of Healthcare Engineering

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Research Article | Open Access

Volume 4 | Article ID 691375 | https://doi.org/10.1260/2040-2295.4.3.409

Chemothermal Therapy for Localized Heating and Ablation of Tumor

Zhong-Shan Deng¹and Jing Liu^1,2

Received01 Sept 2012

Accepted01 Jun 2013

Abstract

Chemothermal therapy is a new hyperthermia treatment on tumor using heat released from exothermic chemical reaction between the injected reactants and the diseased tissues. With the highly minimally invasive feature and localized heating performance, this method is expected to overcome the ubiquitous shortcomings encountered by many existing hyperthermia approaches in ablating irregular tumor. This review provides a relatively comprehensive review on the latest advancements and state of the art in chemothermal therapy. The basic principles and features of two typical chemothermal ablation strategies (acid-base neutralization-reaction-enabled thermal ablation and alkali-metal-enabled thermal/chemical ablation) are illustrated. The prospects and possible challenges facing chemothermal ablation are analyzed. The chemothermal therapy is expected to open many clinical possibilities for precise tumor treatment in a minimally invasive way.

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Copyright © 2013 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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