Table of Contents Author Guidelines Submit a Manuscript
Journal of Healthcare Engineering
Volume 4 (2013), Issue 3, Pages 409-425
http://dx.doi.org/10.1260/2040-2295.4.3.409
Research Article

Chemothermal Therapy for Localized Heating and Ablation of Tumor

Zhong-Shan Deng1 and Jing Liu1,2

1Key Lab of Cryogenics and Beijing Key Lab of CryoBiomedical Engineering, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China
2Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China

Received 1 September 2012; Accepted 1 June 2013

Copyright © 2013 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Liu and Z. S. Deng, Physics of Tumor Hyperthermia, Science Press, Beijing, 2008, (in Chinese).
  2. M. H. Falk and R. D. Issels, “Hyperthermia in oncology,” International Journal of Hyperthermia, vol. 17, pp. 1–18, 2001. View at Google Scholar
  3. G. M. Samaras and A. Y. Cheung, “Microwave hyperthermia for cancer therapy,” CRC Critical Reviews in Bioengineering, vol. 5, pp. 123–184, 1981. View at Google Scholar
  4. B. W. Dong, J. Zhang, P. Liang et al., “Sequential pathological and immunologic analysis of percutaneous microwave coagulation therapy of hepatocellular carcinoma,” International Journal of Hyperthermia, vol. 19, pp. 119–33, 2003. View at Google Scholar
  5. P. Liang, B. Dong, X. Yu et al., “Computer–aided dynamic simulation of microwave-induced thermal distribution in coagulation of liver cancer,” IEEE Transactions on Biomedical Engineering, vol. 48, pp. 821–9, 2001. View at Google Scholar
  6. S. Madersbacher, M. Pedevilla, L. Vingers, M. Susani, and M. Marberger, “Effect of high-intensity focused ultrasound on human prostate cancer in vivo,” Cancer Research, vol. 55, pp. 3346–3351, 1995. View at Google Scholar
  7. E. R. Cordeiro, X. Cathelineau, S. Thüroff, M. Marberger, S. Crouzet, and J. Rosette, “High-intensity focused ultrasound (HIFU) for definitive treatment of prostate cancer,” BJU International, 2012. View at Publisher · View at Google Scholar
  8. B. J. Wood, J. R. Ramkaransingh, T. Fojo, M. M. Walther, and S. K. Libutti, “Percutaneous tumor ablation with radiofrequency,” Cancer, vol. 94, pp. 443–451, 2002. View at Google Scholar
  9. S. Rossi, F. Garbagnati, R. Lencioni et al., “Percutaneous radio-frequency thermal ablation of nonresectable hepatocellular carcinoma after occlusion of tumor blood supply,” Radiology, vol. 217, pp. 119–126, 2000. View at Google Scholar
  10. A. Jordan, P. Wust, H. Fahling, W. John, A. Hinz, and R. Felix, “Inductive heating of ferrimagnetic particles and magnetic fluids - physical evaluation of their potential for hyperthermia,” International Journal of Hyperthermia, vol. 9, pp. 51–68, 1993. View at Google Scholar
  11. A. Jordan, R. Scholz, K. Maier-Hauff et al., “The effect of thermotherapy using magnetic nanoparticles on rat malignant glioma,” Journal of Neuro-Oncology, vol. 78, pp. 7–14, 2006. View at Google Scholar
  12. P. Moroz, S. K. Jones, and B. N. Gray, “The effect of tumour size on ferromagnetic embolization hyperthermia in a rabbit liver tumour model,” International Journal of Hyperthermia, vol. 18, pp. 129–140, 2002. View at Google Scholar
  13. C. Haase and U. Nowak, “Role of dipole-dipole interactions for hyperthermia heating of magnetic nanoparticle ensembles,” Physical Review B, vol. 85:045435, 2012. View at Google Scholar
  14. L. J. Dai, G. R. Hua, A. P. Qian, and Z. Y. Qian, “Investigation on local optical parameters of liver tumors in laser-induced thermotherapy,” Applied Mechanics and Materials, vol. 121–126, pp. 3998–4002, 2012. View at Google Scholar
  15. T. J. Vogl, R. Straub, S. Zangos, M. G. Mack, and K. Eichler, “MR-guided laser-induced thermotherapy (LITT) of liver tumours: experimental and clinical data,” International Journal of Hyperthermia, vol. 20, pp. 713–724, 2004. View at Google Scholar
  16. U. Lindner, J. Trachtenberg, and N. Lawrentschuk, “Focal therapy in prostate cancer: modalities, findings and future considerations,” Nature Reviews Urology, vol. 7, pp. 562–571, 2010. View at Google Scholar
  17. N. Honda, Q. Guo, H. Uchida, H. Ohishi, and Y. Hiasa, “Percutaneous hot saline injection therapy for hepatic tumors: an alternative to percutaneous ethanol injection therapy,” Radiology, vol. 190, pp. 53–57, 1994. View at Google Scholar
  18. R. B. Roemer, “Engineering aspects of hyperthermia therapy,” Annual Review of Biomedical Engineering, vol. 1, pp. 347–376, 1999. View at Google Scholar
  19. P. I. Soares, I. M. Ferreira, R. A. Igreja, C. M. Novo, and J. P. Borges, “Application of hyperthermia for cancer treatment: recent patents review,” Recent Patents on Anti-Cancer Drug Discovery, vol. 7, pp. 64–73, 2012. View at Google Scholar
  20. J. Liu, Z. S. Deng, and W. Rao, “Way to ultra low cost tumor hyperthermia treatment: Targeted high intensity thermochemical ablation therapy,” Science and Technology Review, vol. 26, no. 2, pp. 78–84, 2008, (in Chinese). View at Google Scholar
  21. Z. S. Deng, J. Liu, and Y. X. Zhou, “Tumor hyperthermia method based on exothermic chemical reaction,” China Patent No. 200610083646.6, 2006.
  22. Z. S. Deng and J. Liu, “Minimally invasive thermotherapy method for tumor treatment based on an exothermic chemical reaction,” Minimally Invasive Therapy and Allied Technologies, vol. 16, pp. 341–346, 2007. View at Google Scholar
  23. W. Rao and J. Liu, “Tumor thermal ablation therapy using alkali metals as powerful self heating seeds,” Minimally Invasive Therapy and Allied Technologies, vol. 17, no. 1, pp. 43–49, 2008. View at Google Scholar
  24. W. Rao, J. Liu, Y. X. Zhou, Y. Yang, and H. Zhang, “Anti-tumor effect of sodium-induced thermochemical ablation therapy,” International Journal of Hyperthermia, vol. 24, pp. 675–681, 2008. View at Google Scholar
  25. A. J. Misselt, T. L. Edelman, J. H. Choi, J. C. Bischof, and E. N. Cressman, “A hydrophobic gel phantom for study of thermochemical ablation: initial results using a weak acid and weak base,” Journal of Vascular and Interventional Radiology, vol. 20, pp. 1352–1358, 2009. View at Google Scholar
  26. E. N. Cressman, H. J. Tseng, R. Talaie, and B. M. Henderson, “A new heat source for thermochemical ablation based on redox chemistry: initial studies using permanganate,” International Journal of Hyperthermia, vol. 26, pp. 327–337, 2010. View at Google Scholar
  27. L. A. Freeman, B. Anwer, R. P. Brady et al., “In vitro thermal profile suitability assessment of acids and bases for thermochemical ablation: underlying principles,” Journal of Vascular and Interventional Radiology, vol. 21, pp. 381–385, 2010. View at Google Scholar
  28. J. L. Farnam, B. C. Smith, B. R. Johnson et al., “Thermochemical ablation in an ex-vivo porcine liver model using acetic acid and sodium hydroxide: proof of concept,” Journal of Vascular and Interventional Radiology, vol. 21, pp. 1573–1578, 2010. View at Google Scholar
  29. J. A. Dean, Lange's Chemistry Handbook, McGraw-Hill Professional, New York, 15th edition, 1998.
  30. K. Ohnishi, N. Ohyama, S. Ito, and K. Fujiwara, “Small hepatocellular carcinoma: treatment with US-guided intratumoral injection of acetic acid,” Radiology, vol. 193, pp. 747–752, 1994. View at Google Scholar
  31. L. M. Liu, Y. H. Zhang, and G. Y. Xu, “A study of the feasibility of sodium hydroxide solution as tumor ablation agent,” Chinese Journal of Ultrasound Medicine, vol. 16, pp. 325–327, 2000. View at Google Scholar
  32. C. Acikel, E. Ulkur, and M. M. Guler, “Prolonged intermittent hydrotherapy and early tangential excision in the treatment of an extensive strong alkali burn,” Burns, vol. 27, pp. 293–296, 2001. View at Google Scholar
  33. D. W. Mozingo, A. A. Smith, W. F. McManus, B. A. Pruitt, and A. D. Mason, “Chemical burns,” Journal of Trauma, vol. 28, pp. 642–647, 1988. View at Google Scholar
  34. G. Carlsson, B. Gullberg, and L. Hafström, “Estimation of liver tumor volume using different formulas—an experimental study in rats,” Journal of Cancer Research and Clinical Oncology, vol. 105, pp. 20–23, 1983. View at Google Scholar
  35. W. Rao and J. Liu, “Injectable liquid alkali alloy based tumor thermal ablation therapy,” Minimally Invasive Therapy and Allied Technologies, vol. 18, pp. 30–35, 2009. View at Google Scholar
  36. Y. Harima, K. Nagata, K. Harima, V. V. Ostapenko, Y. Tanaka, and S. Sawada, “A randomized clinical trial of radiation therapy versus thermoradiotherapy in stage IIIB cervical carcinoma,” International Journal of Hyperthermia, vol. 17, pp. 97–105, 2001. View at Google Scholar
  37. J. R. Haaga, A. A. Exner, Y. D. Wang, N. T. Stowe, and P. J. Tarcha, “Combined tumor therapy by using radiofrequency ablation and 5-FU-laden polymer implants: Evaluation in rats and rabbits,” Radiology, vol. 238, pp. 911–918, 2006. View at Google Scholar
  38. M. G. Geeslin and E. N. Cressman, “Thermochemical ablation: a device for a novel interventional concept,” ASME Journal of Medical Devices, vol. 6:015001, 2012. View at Google Scholar
  39. E. N. Cressman, M. M. Shenoi, T. L. Edelman et al., “In vivo comparison of simultaneous versus sequential injection technique for thermochemical ablation in a porcine model,” International Journal of Hyperthermia, vol. 28, pp. 105–112, 2012. View at Google Scholar
  40. E. N. Cressman, M. G. Geeslin, M. M. Shenoi et al., “Concentration and volume effects in thermochemical ablation in vivo: Results in a porcine model,” International Journal of Hyperthermia, vol. 28, pp. 113–121, 2012. View at Google Scholar
  41. R. Deckers, C. Debeissat, P. Y. Fortin, C. Moonen, and F. Couillaud, “Arrhenius analysis of the relationship between hyperthermia and Hsp70 promoter activation: Acomparison between ex vivo and in vivo data,” International Journal of Hyperthermia, vol. 28, pp. 441–450, 2012. View at Google Scholar
  42. X. He, “Thermostability of biological systems: Fundamentals, challenges, and quantification,” The Open Biomedical Engineering Journal, vol. 5, pp. 47–73, 2011. View at Google Scholar