Modelling pH-Optimized Degradation of Microgel-Functionalized Polyesters

Table 1

Parameters used for simulation.

Symbol	Value	Unit	Description	Source
		mol/L	Equilibrium constant of dissociation reaction of COOH at 37°C	[28]
		(mol/L)^2	Equilibrium constant of dissociation reaction of H2O at 37°C	[36]
		1/week	Rate constant of spontaneous ester bond scission	Fit to experiments
			Rate constant for autocatalyzed ester bond scission	Fit to experiments
		mol/L	Equilibrium constant for buffer reaction at 20°C	Fit to experiments
		mol/L	Initial buffer concentration	Fit to experiments
		—	Fraction of volumes occupied by gel and polymer	Derived from experimental procedure
		—	Fraction of volumes occupied by polymer + gel and polymer	—
		m^2/week	Diffusion constant of oligomer in the polymer	[28]
		m^2/week	Diffusion constant of oligomer in water	[37]
		mm	Thickness of polymer foil	Derived from experimental procedure
		mm	Thickness of water column above polymer foil	Derived from experimental procedure