Gene Expression Changes in Long-Term In Vitro Human Blood-Brain Barrier Models and Their Dependence on a Transwell Scaffold Material

Figure 1

Fluorescent immunohistochemistry of biopaper and PET membranes. PECAM-1 (red) is present at BMEC junctions in both models (a, d). GFAP (green) is distributed throughout the astrocyte, showing similar morphology across membrane materials (b, e). Merged images are shown in (c) and (f).