Predicting Interactions between Virus and Host Proteins Using Repeat Patterns and Composition of Amino Acids

Table 10

Results of testing our SVM and DeNovo’s SVM [9] on DeNovo’s dataset of 425 positive and 425 negative PPIs.

Method	Sn (%)	Sp (%)	ACC (%)	PPV (%)	NPV (%)	MCC	AUC
Our SVM	86.35	86.59	86.47	86.56	86.39	0.729	0.926
DeNovo’s SVM	80.71	83.06	81.90	—	—	—	—

Sn: sensitivity, Sp: specificity, Acc: accuracy, PPV: positive predictive value, NPV: negative predictive value, MCC: Matthews correlation coefficient, AUC: the area under the ROC curve, and “—”: not available.