Research Article

Improvement of Adequate Digoxin Dosage: An Application of Machine Learning Approach

Table 6

Performance evaluation of the classifiers for the non-DDI and DDI groups.

GroupMethodSensitivitySpecificityAccuracyAUC

Non-DDIC4.50.705/0.0910.806/0.0780.759/0.0610.784/0.065
CART0.696/0.0950.825/0.0670.765/0.0550.791/0.057
RF0.782/0.0900.888/0.0540 0.839/0.0410.912/0.032
kNN0.619/0.1720.547/0.1620.592/0.0680.606/0.070
LGR0.566/0.1450.715/0.1170.648/0.0780.661/0.097
MLP0.741/0.0910.871/0.0570.809/0.0590.813/0.071

DDIC4.50.701/0.0600.759/0.0500.732/0.0290.774/0.030
CART0.728/0.0510.776/0.0500.754/0.0310.795/0.031
RF0.790/0.0500.817/0.0430.805/0.0270.892/0.020
kNN0.545/0.0940.651/0.0870.602/0.0420.634/0.048
LGR0.464/0.1390.621/0.1450.551/0.0420.556/0.058
MLP0.745/0.0580.799/0.0420.774/0.0370.777/0.051