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Journal of Healthcare Engineering
Volume 2019, Article ID 4230157, 9 pages
Research Article

Development of Electrohysterogram Recording System for Monitoring Uterine Contraction

1College of Life Science and Bioengineering, Beijing University of Technology, Intelligent Physiological Measurement and Clinical Translation, Beijing International Base for Scientific and Technological Cooperation, Beijing 100024, China
2Department of Obstetrics, Peking Union Medical College Hospital, Beijing 100730, China

Correspondence should be addressed to Dongmei Hao; nc.ude.tujb@iemgnodoah

Received 3 March 2019; Revised 21 May 2019; Accepted 2 June 2019; Published 1 July 2019

Academic Editor: Emanuele Rizzuto

Copyright © 2019 Dongmei Hao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Uterine contraction (UC) is an important clinical indictor for monitoring uterine activity. The purpose of this study is to develop a portable electrohysterogram (EHG) recording system (called PregCare) for monitoring UCs with EHG signals. The PregCare consisted of sensors, a signal acquisition device, and a computer with application software. Eight-channel EHG signals, the tocodynamometry (TOCO) signal, and maternal perception were recorded simultaneously by the signal acquisition device controlled by the computer via Bluetooth. PregCare was firstly evaluated by a signal simulator. Its relative error (RE) and coefficient of variation (CV) were calculated, and its agreement with the commercial instrument PowerLab was assessed by Bland–Altman plots. After that, PregCare was applied to 20 pregnant women in a hospital to record their EHG signals. These EHG signals were preprocessed and segmented into UCs and non-UCs. Then, the EHG features corresponding to UCs and non-UCs were extracted, respectively, including power spectral density (PSD), root mean square (RMS), peak frequency (PF), median frequency (MDF), and sample entropy (SamEn). One-way ANOVA was employed to assess the difference between UCs and non-UCs. The results show that RE and CV were less than 8% and 0.03%, respectively, which indicated the high accuracy and repeatability of PregCare. The small differences of mean and standard deviation indicated the high agreement between PregCare and PowerLab. Besides, the PSD of UCs was much larger than non-UCs between 0 and 0.7 Hz. RMS of UCs was significantly larger than non-UCs (). PF and SamEn of UCs were significantly smaller than non-UCs (). In conclusion, the developed EHG recording system was able to record EHG signals reliably. It has the advantages of portability, low power consumption, and wireless transmission, which can be used for long-term monitoring of UCs and prediction of the preterm delivery.