Retrospective Analysis of Microbial Colonization Patterns in Central Venous Catheters, 2013–2017

Table 2

Etiology of the CVC colonization and CALBSI episodes.

Microorganism	Colonization (n = 379)	CALBSI (n = 107)
Gram-positive bacteria, n (%)
S. aureus	25 (6.6)	14 (13.1)
S. epidermidis	43 (11.3)	7 (6.5)
S. haemolyticus	35 (9.2)	7 (6.5)
Other CoNS	31 (8.2)	7 (6.5)
Enterococcus	8 (2.1)	2 (1.9)
Corynebacterium	6 (1.6)	1 (0.9)
Others	4 (1.1)	1 (0.9)
Gram-negative bacteria, n (%)
Acinetobacter	75 (19.8)	25 (23.4)
Pseudomonas species	37 (9.8)	12 (11.2)
Klebsiella species	14 (3.7)	3 (2.8)
Colibacter	12 (3.2)	3 (2.8)
Enterobacter spp.	11 (2.9)	5 (4.7)
Others	19 (5.0)	—
Fungi, n (%)
Candida albicans	39 (10.3)	13 (12.1)
Candida parapsilosis	9 (2.4)	5 (4.7)
Candida glabrata	6 (1.6)	1 (0.9)
Others	5 (1.3)	1 (0.9)

CVC, central venous catheter; CLABSI, central line-associated bloodstream infection; CoNS, coagulase-negative staphylococci. The data in the table are presented as n (%), which refer to the number of isolated organism (n) and the percentage of different isolated organisms (%), respectively. The total number of isolated organisms was 379 (18.7%). Gram-negative bacteria with 44.4% were predominate among the total colonization bacteria on the CVC surfaces, followed by Gram-positive bacteria (40.1%) and fungi (15.6%). A total of 107 (5.3%) isolated organisms from CVCs were associated with a diagnosis of CLABSI. The most common organisms in causing CLABSI were Acinetobacter (23.4%), S. aureus (13.1%), and Candida albicans (12.1%).