Gene Characteristics and Prognostic Values of m⁶A RNA Methylation Regulators in Nonsmall Cell Lung Cancer

Table 2

Clinical features of patients with NSCLC who are with or without genetic alterations of m⁶A regulators.

Parameters		With mutation and/or CNVs	Without mutation and/or CNVs	value
Age	≤60	90	176	0.217
	>60	223	524
Gender	Female	123	283	0.787
	Male	190	417
Primary diagnosis	Acinar cell carcinoma	6	16	0.07
	Adenocarcinoma, NOS	102	210
	Adenocarcinoma with mixed subtypes	37	71
	Basaloid squamous cell carcinoma	5	9
	Bronchiolo-alveolar carcinoma, mucinous	2	3
	Bronchiolo-alveolar adenocarcinoma, NOS	1	2
	Bronchiolo-alveolar carcinoma, nonmucinous	6	12
	Clear cell adenocarcinoma, NOS	1	1
	Micropapillary carcinoma, NOS	0	3
	Mucinous adenocarcinoma	1	12
	Papillary adenocarcinoma, NOS	6	16
	Papillary squamous cell carcinoma	1	3
	Signet ring cell carcinoma	0	1
	Solid carcinoma, NOS	2	4
	Squamous cell carcinoma, keratinizing, NOS	3	9
	Squamous cell carcinoma, small cell, nonkeratinizing	1	3
	Squamous cell carcinoma, NOS	139	325
Tumor stage	Not reported	3	8	0.001
	Stage I-II	242	559
	Stage III-IV	68	133
Tissue or organ of origin	Lower lobe, lung	99	251	0.137
	Lung, NOS	14	37
	Main bronchus	4	5
	Middle lobe, lung	14	23
	Overlapping lesion of lung	6	5
	Upper lobe, lung	176	379

NOS, not otherwise specified.