Research Article
Gene Characteristics and Prognostic Values of m6A RNA Methylation Regulators in Nonsmall Cell Lung Cancer
Table 2
Clinical features of patients with NSCLC who are with or without genetic alterations of m6A regulators.
| Parameters | | With mutation and/or CNVs | Without mutation and/or CNVs | value |
| Age | ≤60 | 90 | 176 | 0.217 | >60 | 223 | 524 | |
| Gender | Female | 123 | 283 | 0.787 | Male | 190 | 417 | |
| Primary diagnosis | Acinar cell carcinoma | 6 | 16 | 0.07 | Adenocarcinoma, NOS | 102 | 210 | | Adenocarcinoma with mixed subtypes | 37 | 71 | | Basaloid squamous cell carcinoma | 5 | 9 | | Bronchiolo-alveolar carcinoma, mucinous | 2 | 3 | | Bronchiolo-alveolar adenocarcinoma, NOS | 1 | 2 | | Bronchiolo-alveolar carcinoma, nonmucinous | 6 | 12 | | Clear cell adenocarcinoma, NOS | 1 | 1 | | Micropapillary carcinoma, NOS | 0 | 3 | | Mucinous adenocarcinoma | 1 | 12 | | Papillary adenocarcinoma, NOS | 6 | 16 | | Papillary squamous cell carcinoma | 1 | 3 | | Signet ring cell carcinoma | 0 | 1 | | Solid carcinoma, NOS | 2 | 4 | | Squamous cell carcinoma, keratinizing, NOS | 3 | 9 | | Squamous cell carcinoma, small cell, nonkeratinizing | 1 | 3 | | Squamous cell carcinoma, NOS | 139 | 325 | |
| Tumor stage | Not reported | 3 | 8 | 0.001 | Stage I-II | 242 | 559 | | Stage III-IV | 68 | 133 | |
| Tissue or organ of origin | Lower lobe, lung | 99 | 251 | 0.137 | Lung, NOS | 14 | 37 | | Main bronchus | 4 | 5 | | Middle lobe, lung | 14 | 23 | | Overlapping lesion of lung | 6 | 5 | | Upper lobe, lung | 176 | 379 | |
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NOS, not otherwise specified.
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