[Retracted] ADAM8 Activates NLRP3 Inflammasome to Promote Cerebral Ischemia-Reperfusion Injury

Figure 3

ADAM8 induced cerebral cortex injury induced in cerebral ischemia-reperfusion mice. (a) After reperfusion for 24 hours, neurological deficits of mice were assessed, n = 8 mice per group. (b) After reperfusion for 24 hours, brain sections of the indicated group were stained with 2,3,5-triphenyltetrazolium chloride (left) and analysis of infarct volume (right) was performed, n = 5 mice per group. (c) After reperfusion for 24 hours, cerebral blood flow of mice was recorded, n = 4 mice per group. (d) Nissl staining assays were performed in ischemic brain sections at 24 hours after I-R injury, n = 4 mice per group. All values are expressed as the mean ± SD. , , vs. Sham Scramble shRNA group. , , vs. MCAO Scramble shRNA group.

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