[Retracted] ADAM8 Activates NLRP3 Inflammasome to Promote Cerebral Ischemia-Reperfusion Injury

<div>ADAM8 promoted the apoptosis of cerebral cortical neurons in cerebral ischemia and reperfusion mice. (a) Cleaved caspase-3 in the penumbra was detected by western blotting after reperfusion for 24 hours, <i>n</i> = 4 mice per group. (b) TUNEL and immunofluorescence analysis of the apoptosis cerebral in cortex penumbra at 24 hours after I-R injury. The magnification was 40x and the scale bar was 50 <i>μ</i>m, <i>n</i> = 3 mice per group. 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Journal of Healthcare Engineering

fig4

Figure 4

Figure 4: [Retracted] ADAM8 Activates NLRP3 Inflammasome to Promote Cerebral Ischemia-Reperfusion Injury 