[Retracted] Identification of ZEB2 as an Immune-Associated Gene in Endometrial Carcinoma and Associated with Macrophage Infiltration by Bioinformatic Analysis

Figure 6

Somatic mutations of ZEB2 in EC patients with clinical relevance. (a) Oncoplot of the most frequently mutated genes (PTEN, PIK3CA, TP53, CTNNB1, POLE) along with ZEB2 in patients of the TCGA-UCEC dataset. Each cell represents a sample with a different gene. Colored squares show mutated genes, while grey squares show no mutated genes. The mutation types were added as annotations at the bottom. (b) Lollipop plot showing variant distributions of human ZEB2 (NM_014795) in TCGA-UCEC. The colored boxes were specific functional domains. The frequencies of variants were shown as different lines. Kaplan–Meier plot comparing ZEB2 genomic alternation status with the probability of overall survival (OS) (c) and disease-free survival (DFS) (d) for patients downloading from cBioPortal. DFS, disease-free survival; OS, overall survival; TCGA, the Cancer Genome Atlas; UCEC, Uterine Corpus Endometrial Carcinoma; ZEB2, Zinc finger E-box binding homeobox 2. Two-tailed paired Student t-test values indicate statistical significance (, ).

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