Efficacy of Whole-Body Vibration Training on Brain-Derived Neurotrophic Factor, Clinical and Functional Outcomes, and Quality of Life in Women with Fibromyalgia Syndrome: A Randomized Controlled Trial
Table 5
Effects of 6 weeks of intervention and change from baseline on biomarker levels, functional outcomes, and clinical outcomes in control and whole-body vibration training groups.
Outcome
CG (week 6)
Δ (change from baseline)
IG (week 6)
Δ (change from baseline)
Interaction value
Partial η2
Power
Biomarker(ng/mL)
BDNF
1.80 (1.42 to 2.19)
−0.58 (−0.39 to −0.77)
2.58 (1.83 to 3.34)
0.23 (0.03 to 0.43)
0.045
0.81
0.99
Functional outcomes
6MWT, m
415.40 (396.63 to 434.17)
−11.87 (−30.80 to 7.06)
470.35 (445.68 to 495.02)
22.59 (3.68 to 41.50)
0.010
0.88
1.0
STS, rep.
8.67 (7.22 to 10.12)
0.40 (−0.22 to 1.02)
10.41 (9.16 to 11.66)
2.41 (1.04 to 3.78)
0.011
0.88
1.0
Clinical outcomes
FIQ, score
68.79 (62.23 to 75.35)
2.12 (−4.45 to 8.69)
45.12 (34.99 to 55.25)
−27.41 (−34.81 to 20.01)
0.001
0.97
1.0
Pain, VAS
5.91 (4.78 to 7.04)
0.15 (−1.44 to 1.74)
3.46 (2.06 to 4.86)
3.46 (2.06 to 4.86)
0.008
0.93
1.0
PSQI, score
14.13 (12.37 to 15.89)
0.80 (−0.64 to 2.24)
7.18 (5.18 to 9.18)
−5.00 (−7.04 to 2.96)
0.001
0.38
0.34
BDI, score
25.20 (19.40 to 31.00)
0 (−1.26 to 1.26)
14.76 (9.10 to 20.42)
−6.88 (−12.17 to −1.59)
0.017
0.86
1.0
Values are means (95% confidence interval). CG: control group (n = 15). IG: intervention group (n = 17). BDNF: brain-derived neurotrophic factor; 6MWT: six-minute walk test; STS: sit-to-stand test; rep.: repetition; FIQ: Fibromyalgia Impact Questionnaire; VAS: visual analog scale; PSQI: Pittsburgh Sleep Quality Index; BDI: Beck Depression Inventory. Interaction, group x time. Eta partial, η2.
