Research Article

[Retracted] To Investigate the Effect of Glucocorticoids on Blood Loss during and after First Total Hip Arthroplasty and Its Safety Meta-Analysis

Table 1

General condition of included study patients.

Investigators and yearsT/C (people)Mean age (years) (T/C)InterveneDrainage tubeTransfusion criteriaProsthesis type

Martin [12]25/2562.96/63.92100 mg hydrocortisone, 2 h before operation and push still + 8 h after the second doseNot usedHb < 7NS
Wei [13]102/10060.2/63.910 mg dexamethasone, 1 h preoperative static push + second dose during surgeryThey were opened after 30 min of clipping and removed 24 h after surgeryHb < 9Cementless prostheses
Alshryda [14]80/8166/63100 mg hydrocortisone, 2 h before operation push + 8 h after second dose + 8 h after third doseNSNSNS
Yue [15]52/4960.9/63.78 mg or 16 mg dexamethasone at the end of surgery and pushed to restThey were opened after 30 min of clipping and removed 24 h after surgeryHb < 7Cementless prostheses
Jiajing Ye [16]40/4071.5/71.3With 125 mg methylprednisolone, i.p.They were opened 3 h after clipping and removed 24 h after surgeryHb < 7.5Cementless prostheses
Ding, min [17]30/3060.00/61.00100 mg hydrocortisone, 2 h before operation push + 8 h after second dose + 8 h after third doseNot usedHb < 8DePuy joints
Yin Han [18]30/3050.00/53.56100 mg dexamethasone, and pushed statically before anesthesiaThey were opened after 6 h of clipping and removed at 48 h after surgeryHb < 7Biotype prosthesis
Yan, Liang [19]107/10754.10/62.2310 mg dexamethasone, i.p.Not usedHb < 7Cementless prostheses
Fanfucheng [20]56/4466.04/66.50100 mg hydrocortisone, 2 h before operation and push still + 8 h after the second doseThey were opened after 2 h of clipping and removed 24 h after surgeryHb < 7Cementless prostheses
Yuan, Xiaowei [21]40/4076.90/76.8610 mg dexamethasone, 1 h preoperative static push + second dose during surgeryThe interval was 1 h and was removed 48 h after surgery. They were removed 48 h after surgeryHb < 9DePuy total hip instrumentation

T: glucocorticoid application, C: control group, NS: not mentioned, Hb: hemoglobin.