[Retracted] Study on Toll-Like Receptor 2-Mediated Inflammation-Induced Familial Hypertension Combined with Hyperlipemia and Its Mechanism

Figure 5

Changes in NF-κB pathway protein, MAP, lipid level, and apolipoprotein levels, TLR2, and inflammatory factors after blocking the NF-κB pathway. (a) IKK and protein expression levels of the wild-high fat-Ang II-BAY11-7082 group were significantly lower than those of the wild-high fat-Ang II group. (b) MAP in the wild-high fat-Ang II-BAY11-7082 group significantly decreased compared with the wild-high fat-Ang II group. (c) The TC and LDL in serum significantly decreased in the wild-high fat-Ang II group and wild-high fat-Ang II group, with no significant statistical difference between triglyceride and high-density lipoprotein in the two groups. (d) The concentrations of IL-1β and TNF-α in serum significantly decreased in the wild-high fat-Ang II-BAY11-7082 group compared with the wild-high fat-Ang II group, with no statistical difference in the concentrations of TLR2, IL-6, and CCL2 (n = 5; ).

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