[Retracted] circRNA LDLRAD3 Enhances the Malignant Behaviors of NSCLC Cells via the miR-20a-5p-SLC7A5 Axis Activating the mTORC1 Signaling Pathway

Figure 1

LDLRAD3 exerted oncogenic roles and it sponged miR-20a-5p. (a) The expression level of LDLRAD3 in NSCLC tissues and tumor-adjacent normal tissues was analyzed by qRT-PCR. (b) The survival time of patients with the LDLRAD3 expression level was higher or lower than the median. (c) The expression level of LDLRAD3 in NSCLC cell lines and a normal cell line was analyzed by qRT-PCR. (d) The expression level of LDLRAD3 in transfected A549 and H1299 cell lines was analyzed by qRT-PCR. (e) The proliferation of transfected cells was analyzed by CCK-8 assay. (f) The migration of cells was analyzed by transwell assay. (g) The invasion of cells was analyzed by transwell assay. (h) The expression level of miR-20a-5p in NSCLC tissues and tumor-adjacent normal tissues was analyzed by qRT-PCR. (i) The correlation between the expression levels of LDLRAD3 and miR-20a-5p in NSCLC tissues was analyzed by Spearman’s correlation test. (j) The binding site of LDLRAD3 on miR-20a-5p was predicted by ENCORI. (k) The binding relationship between LDLRAD3 and miR-20a-5p was verified by the DLR assay. (l) The expression level of miR-20a-5p in transfected A549 and H1299 cell lines was analyzed by qRT-PCR. and .