Comprehensive Analysis of Prognostic Value and Immune Infiltration of IGFBP Family Members in Glioblastoma

Table 3

Multivariate analysis of the correlation of IGFBPs expression and immune infiltrates with OS in GBM.

	Coef	HR (95%CI_l−95%CI_u)	value	Sig
Age	0.027	1.027(1.018–1.036)	0.000
IGFBP6	0.146	1.158 (1.036–1.293)	0.010
IGFBP2	0.110	1.117 (1.016–1.227)	0.022
Dendritic	0.384	1.468 (0.964–2.238)	0.074
raceWhite	0.603	1.828 (0.739–4.523)	0.192
IGFBP4	−0.084	0.920 (0.809–1.045)	0.200
B cell	−0.425	0.654 (0.339–1.261)	0.205
Neutrophil	0.608	1.836 (0.675–4.992)	0.234
Gender (male)	0.079	1.082(0.859–1.363)	0.504
CD8_T cell	0.156	1.169 (0.704–1.943)	0.546
IGFBP1	−0.040	0.961 (0.842–1.097)	0.554
Purity	0.211	1.235 (0.610–2.503)	0.557
IGFBP3	−0.025	0.975 (0.893–1.065)	0.572
Macrophage	0.231	1.259 (0.565–2.809)	0.573
raceBlack	0.234	1.264(0.454–3.522)	0.654
CD4_T cell	−0.082	0.922 (0.398–2.133)	0.849
IGFBP5	0.002	1.002 (0.869–1.154)	0.982

; .