Research Article
Comprehensive Analysis of Prognostic Value and Immune Infiltration of IGFBP Family Members in Glioblastoma
Table 3
Multivariate analysis of the correlation of IGFBPs expression and immune infiltrates with OS in GBM.
| | Coef | HR (95%CI_l−95%CI_u) | value | Sig |
| Age | 0.027 | 1.027(1.018–1.036) | 0.000 | | IGFBP6 | 0.146 | 1.158 (1.036–1.293) | 0.010 | | IGFBP2 | 0.110 | 1.117 (1.016–1.227) | 0.022 | | Dendritic | 0.384 | 1.468 (0.964–2.238) | 0.074 | | raceWhite | 0.603 | 1.828 (0.739–4.523) | 0.192 | | IGFBP4 | −0.084 | 0.920 (0.809–1.045) | 0.200 | | B cell | −0.425 | 0.654 (0.339–1.261) | 0.205 | | Neutrophil | 0.608 | 1.836 (0.675–4.992) | 0.234 | | Gender (male) | 0.079 | 1.082(0.859–1.363) | 0.504 | | CD8_T cell | 0.156 | 1.169 (0.704–1.943) | 0.546 | | IGFBP1 | −0.040 | 0.961 (0.842–1.097) | 0.554 | | Purity | 0.211 | 1.235 (0.610–2.503) | 0.557 | | IGFBP3 | −0.025 | 0.975 (0.893–1.065) | 0.572 | | Macrophage | 0.231 | 1.259 (0.565–2.809) | 0.573 | | raceBlack | 0.234 | 1.264(0.454–3.522) | 0.654 | | CD4_T cell | −0.082 | 0.922 (0.398–2.133) | 0.849 | | IGFBP5 | 0.002 | 1.002 (0.869–1.154) | 0.982 | |
|
|
|