[Retracted] Association of Paraoxonase 1 Gene Polymorphisms with the Risk of Breast Fibroadenoma and Breast Cancer in the Females of Guangxi, China
Table 3
Genotype and allele frequencies of candidate SNPs in patients and control individuals.
Controls
BF
BC
SNPs
n = 98 (%)
n = 55 (%)
OR (95% CI)
POR
n = 80 (%)
OR (95% CI)
POR
rs662 genotypes
GG
42 (42.9%)
22 (40.0%)
1.00ref
30 (37.5%)
1.00ref
AA
11 (11.2%)
25 (45.5%)
6.609 (2.077–21.022)
0.001
26 (32.5%)
3.862 (1.521–9.808)
0.004
GA
45 (45.9%)
8 (14.5%)
0.497 (0.161–1.532)
0.223
24 (30.0%)
0.569 (0.251–1.290)
0.177
GA + AA
56 (57.1%)
33 (60)
1.586 (0.659–3.818)
0.304
50 (62.5%)
1.193 (0.599–2.379)
0.615
rs662 alleles
G
129 (65.8%)
52 (47.3%)
1.00ref
84 (52.5%)
1.00ref
A
67 (34.2%)
58 (52.7%)
2.854 (1.529–5.328)
0.001
76 (47.5%)
1.878 (1.162–3.034)
0.01
rs705382 genotypes
CC
21 (21.4%)
14 (25.5%)
1.00ref
22 (27.5%)
1.00ref
GG
24 (24.5%)
11 (20.0%)
0.657 (0.187–2.312)
0.513
23 (28.8%)
0.925 (0.365–2.343)
0.869
CG
53 (54.1%)
30 (54.5%)
1.111 (0.387–3.195)
0.844
35 (43.8%)
0.579 (0.254–1.320)
0.194
CG + GG
77 (78.6%)
41 (74.5%)
0.949 (0.347–2.592)
0.919
58 (72.5%)
0.683 (0.317–1.471)
0.33
rs705382 allele
C
95 (48.5%)
58 (52.7%)
1.00ref
79 (49.4%)
1.00ref
G
101 (51.5%)
52 (47.3%)
0.826 (0.459–1.487)
0.524
81 (50.6%)
0.963 (0.603–1.538)
0.875
For rs662, codominant model: AG vs GG, GG vs GG, and dominant model: GA + AA. For rs705382, codominant model: CG vs CC, GG vs CC, and dominant model: CG + GG, adjusted for age, smoking, drinking, and BMI.
