Research Article
Mechanism of Zhinao Capsule in Treating Alzheimer’s Disease Based on Network Pharmacology Analysis and Molecular Docking Validation
Table 2
Results of the molecular docking of four key targets with components.
| Target | Component | MOL ID | Binding energy (kcal/mol) |
| CASP3 | Beta-sitosterol | MOL002714 | −8.15 | CASP3 | Naringenin | MOL004328 | −7.38 | CASP3 | Luteolin | MOL000006 | −7.34 | CASP3 | Quercetin | MOL000098 | −7.21 | CASP3 | Baicalein | MOL002714 | −7.12 | CASP3 | Kaempferol | MOL000422 | −7.08 | TNF-α | Quercetin | MOL000098 | −7.97 | TNF-α | Kaempferol | MOL000422 | −7.58 | TNF-α | Luteolin | MOL000006 | −7.56 | VEGFA | Baicalein | MOL002714 | −7.81 | VEGFA | Quercetin | MOL000098 | −7.56 | VEGFA | Diosgenin | MOL000546 | −7.39 | VEGFA | Luteolin | MOL000006 | −7.33 | MAPK1 | Quercetin | MOL000098 | −7.65 | MAPK1 | Luteolin | MOL000006 | −7.44 | MAPK1 | Naringenin | MOL004328 | −7.23 |
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