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| Gene symbol | Full name | Function |
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| CCL5 | C-C motif chemokine ligand 5 | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. |
| CCR7 | C-C motif chemokine receptor 7 | Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. |
| CD2 | CD2 molecule | The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. |
| CD27 | CD27 molecule | The protein encoded by this gene is a member of the TNF-receptor superfamily. |
| CD274 | CD274 molecule | This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. |
| CD3D | CD3d molecule | The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. |
| GNLY | Granulysin | The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. |
| GZMA | Granzyme A | GZMA is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. |
| GZMH | Granzyme H | This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. |
| GZMK | Granzyme K | This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. |
| IL2RB | Interleukin 2 receptor subunit beta | Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. |
| IL7R | Interleukin 7 receptor | The protein encoded by this gene is a receptor for interleukin 7 (IL7). |
| ITK | IL2 inducible T cell kinase | This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. |
| KLRB1 | Killer cell lectin like receptor B1 | Plays an inhibitory role on natural killer (NK) cells cytotoxicity. |
| PRF1 | Perforin 1 | This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. |
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