[Retracted] MicroRNA-517c Functions as a Tumor Suppressor in Hepatocellular Carcinoma via Downregulation of KPNA2 and Inhibition of PI3K/AKT Pathway
Table 1
Correlation of miR-517c expression with the clinicopathological characteristics of the HCC patients.
Clinicopathological features
Cases (n = 47)
miR-517ca expression
value
High (n = 19)
Low (n = 28)
Age (years)
0.2138
>60
24
10
14
≤60
23
9
14
Gender
0.3141
Male
24
8
16
Female
23
11
12
Tumor size (cm)
0.0124
≥5.0
23
4
19
<5.0
24
15
9
TNM stage
0.0209
I-II
25
15
10
III
22
4
18
AFP (ng/ml)
0.1620
<400
23
13
10
>400
24
6
18
HBV-negative
21
7
14
0.0958
HBV-positive
26
12
14
Presence of venous invasion
23
3
20
0.0203
Absence of venous invasion
24
16
8
Cirrhosis
0.0687
Yes
29
12
17
No
18
7
11
BCLC stage
0.0105
0-A
21
14
7
B-C
26
5
21
TNM: tumor-node-metastasis; AFP: alpha-fetoprotein; HBV: hepatitis B virus; BCLC: Barcelona Clinic liver cancer. aThe mean expression level of miR-517c was used as the cutoff; statistically significant.
