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| No. | Author | Object | Advantages | Challenges |
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| 1 | Cederholm et al. [13] | To estimate the risks of fatal/nonfatal coronary heart disease (CHD), stroke, and cardiovascular disease (CVD) according to the SBP in an observational study of patients with type 2 diabetes | The follow-up data captured were based on national registries of morbidity and mortality, which have a high quality and coverage rate | The type and amount of antihypertensive drugs used in the analysis were unclear |
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| 2 | Portegies et al. [14] | To identify the long-term trajectories of blood pressure in a population-based study and to examine the risk of stroke within those trajectories | (1) The study population was large | (1) The number of stroke subtypes examined was too small |
| (2) The data were comprehensive | (2) We did not have information about blood pressure at earlier ages |
| (3) The follow-up period was long |
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| 3 | Xu et al. [21] | To describe the blood pressure trajectory of patients with ischemic stroke with high blood pressure in the first 7 days of admission and to examine its relationship with clinical outcomes | It highlights the superiority of SBP trajectories over BP levels and single-day variations using a single value | (1) Small sample size |
| (2) Changes in blood pressure during the acute phase caused by BP-lowering medications were not considered |
| (3) The results may be influenced by selection bias and potential confounding factors |
| 4 | Tanaka et al. [27] | The objective of this study was to highlight the heterogeneity of temporal SBP changes in the ATACH-2 trial using GBTM and to analyze the associations with the outcomes of acute intracerebral hemorrhage | The determination of the SBP trajectory grouping was less arbitrary | The results may not be totally applicable to lobar ICH patients because of the low proportion of lobar ICH in ATACH-2 |
| 5 | Lee et al. [28] | To describe the patterns of BP changes up to 1 year after ischemic stroke using group-based trajectory models and to explore the associations between the BP trajectory group and poststroke cardiovascular outcomes | The results of the study are robust | (1) The sample selection is biased |
| (2) The generalizability of the results of the study to the entire population of patients with stroke may be limited |
| 6 | Wang et al. [29] | To investigate whether the long-term trajectories of a high SBP can further predict the risk of all-cause death in Chinese adults | Large sample size | (1) A specific classification of the causes of death is not given |
| (2) The follow-up period was relatively short for SBP trajectory patterns |
| 7 | Kim et al. [30] | To explore the relationship between different trajectory groups and stroke characteristics and the risk of subsequent recurrent vascular events | (1) This is the first study to apply group-based trajectory models to investigate the heterogeneity in SBP trajectories during the acute stroke period | (1) An analysis of increasing antihypertensive drugs, as well as other influencing factors, was not performed |
| (2) The findings may be generalizable to patients with acute stroke in Korea | (2) Studies may have limited generalizability |
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