Quantitative Scintigraphy Evaluated the Relationship between 131I Therapy and Salivary Glands Function in DTC Patients: A Retrospective Analysis
Table 2
Comparison of salivary gland function in patients before secondary treatmen.
Scintigraphic parameters
Male under 55 years
Male older than or equal to 55 years
Female under 55 years
Female older than or equal to 55 years
Damage before treatment
After firsttreatment
No damage before treatment
After firsttreatment
Damage before treatment
After firsttreatment
No damage before treatment
After firsttreatment
Damage before treatment
After firsttreatment
No damage before treatment
After firsttreatment
Damage before treatment
After firsttreatment
No damage before treatment
After firsttreatment
RP
Number:6
Number:83
Number:2
Number:32
Number:13
Number:244
Number:4
Number:74
UF
0.039 (0.027–0.071)
0.057 (0.025–0.093)
0.173
0.043 (0.031–0.054)
0.039 (0.030–0.058)
0.806
0.016 (0.011–0.014)
0.018 (0.013–0.014)
0.180
0.047 (0.026–0.066)
0.043 (0.025–0.056)
0.100
0.023 (0.016–0.049)
0.043 (0.022–0.051)
0.116
0.043 (0.032–0.057)
0.038 (0.030–0.049)
0.000
0.025 (0.010–0.044)
0.027 (0.015–0.036)
0.715
0.047 (0.034–0.058)
0.037 (0.029–0.057)
0.218
UI
1.792 (1.337–2.293)
2.448 (1.117–4.080)
0.116
1.814 (1.425–2.377)
1.806 (1.424–2.423)
0.799
0.967 (0.589–0.862)
0.960 (0.707–0.732)
0.655
1.787 (1.176–2.175)
1.685 (0.974–1.949)
0.104
1.714 (1.221–2.363)
1.946 (1.364–2.643)
0.133
2.105 (1.621–2.618)
1.920 (1.467–2.369)
0.000
1.314 (0.774–2.224)
1.169 (0.836–1.466)
0.465
1.868 (1.514–2.604)
1.712 (1.349–2.410)
0.243
EF
0.109 (0.070–0.218)
0.501 (0.292–0.613)
0.046
0.473 (0.412–0.546)
0.461 (0.354–0.539)
0.064
0.306 (0.190–0.270)
0.268 (0.195–0.207)
0.655
0.444 (0.361–0.488)
0.396 (0.302–0.513)
0.161
0.316 (0.118–0.437)
0.465 (0.241–0.521)
0.055
0.496 (0.428–0.560)
0.467 (0.404–0.533)
0.001
0.176 (0.091–0.255)
0.359 (0.143–0.473)
0.144
0.508 (0.444–0.556)
0.475 (0.409–0.541)
0.113
LP
Number:3
Number:86
Number:2
Number:32
Number:17
Number:240
Number:8
Number:70
UF
0.034 (0.019–0.048)
0.036 (0.016–0.040)
0.593
0.039 (0.030–0.050)
0.036 (0.027–0.050)
0.113
0.023 (0.011–0.023)
0.031 (0.012–0.034)
0.180
0.044 (0.034–0.072)
0.045 (0.025–0.067)
0.197
0.023 (0.013–0.036)
0.032 (0.020–0.048)
0.407
0.038 (0.029–0.053)
0.036 (0.028–0.048)
0.000
0.020 (0.011–0.042)
0.031 (0.023–0.047)
0.069
0.044 (0.030–0.061)
0.035 (0.024–0.047)
0.000
UI
0.805 (0.724–1.409)
1.197 (0.588–1.633)
0.285
1.874 (1.346–2.240)
1.689 (1.288–2.142)
0.079
1.072 (0.594–1.014)
1.312 (0.732–1.237)
0.180
1.858 (1.388–2.379)
1.567 (1.261–2.528)
0.443
1.465 (1.308–2.291)
1.770 (1.368–2.305)
0.227
2.013 (1.569–2.548)
1.841 (1.464–2.347)
0.000
1.464 (0.940–2.044)
1.560 (1.012–2.049)
0.401
2.050 (1.427–2.531)
1.630 (1.243–2.134)
0.005
EF
0.124 (0.104–0.154)
0.418 (0.132–0.443)
0.109
0.486 (0.427–0.544)
0.465 (0.377–0.549)
0.043
0.198 (0.053–0.244)
0.390 (0.227–0.358)
0.655
0.440 (0.359–0.511)
0.397 (0.304–0.498)
0.061
0.225 (0.120–0.357)
0.383 (0.339–0.467)
0.001
0.494 (0.420–0.564)
0.468 (0.394–0.535)
0.000
0.188 (0.167–0.240)
0.390 (0.261–0.487)
0.208
0.504 (0.432–0.588)
0.472 (0.366–0.535)
0.008
RS
Number:9
Number:80
Number:3
Number:31
Number:39
Number:218
Number:5
Number:73
UF
0.033 (0.023–0.049)
0.024 (0.021–0.046)
0.767
0.058 (0.042–.0766)
0.048 (0.038–0.062)
0.000
0.023 (0.023–0.030)
0.036 (0.021–0.036)
0.285
0.057 (0.048–0.067)
0.045 (0.038–0.063)
0.011
0.034 (0.028–0.042)
0.032 (0.026–0.049)
0.944
0.047 (0.035–0.061)
0.042 (0.033–0.052)
0.000
0.010 (0.009–0.026)
0.019 (0.015–0.029)
0.345
0.062 (0.050–0.078)
0.055 (0.047–0.070)
0.006
UI
2.156 (1.363–2.733)
1.662 (1.297–2.530)
0.767
2.984 (2.540–3.957)
2.736 (2.209–3.705)
0.016
1.736 (0.886–1.989)
1.883 (1.282–2.093)
0.285
3.074 (2.399–3.531)
2.604 (2.127–3.239)
0.050
1.780 (1.358–2.158)
2.018 (1.582–2.324)
0.024
2.490 (2.002–3.307)
2.401 (1.997–2.945)
0.001
1.205 (.699–1.960)
1.402 (0.846–1.937)
0.893
3.034 (2.607–3.986)
2.923 (2.405–3.742)
0.008
EF
0.171 (0.157–0.190)
0.194 (0.175–0.254)
0.066
0.388 (0.313–0.470)
0.347 (0.256–0.444)
0.020
0.152 (0.038–0.281)
0.196 (0.050–0.358)
0.593
0.374 (0.304–0.421)
0.339 (0.238–0.400)
0.264
0.157 (0.116–0.181)
0.255 (0.180–0.341)
0.000
0.377 (0.285–0.457)
0.344 (0.264–0.413)
0.000
0.132 (0.072–0.150)
0.174 (0.090–0.257)
0.043
0.432 (0.338–0.520)
0.383 (0.290–0.488)
0.005
LS
Number:10
Number:79
One case
Number:31
Number:50
Number:207
Number:7
Number:71
UF
0.027 (0.020–0.034)
0.025 (0.021–0.041)
0.241
0.052 (0.044–0.071)
0.045 (0.035–0.059)
0.000
0.061 (0.045–0.069)
0.048 (0.040–0.066)
0.010
0.029 (0.024–0.035)
0.029 (0.023–0.037)
0.490
0.045 (0.035–0.060)
0.042 (0.032–0.053)
0.000
0.017 (0.012–0.033)
0.022 (0.018–0.034)
0.398
0.061 (0.044–0.082)
0.050 (0.036–0.062)
0.000
UI
1.882 (1.247–2.158)
1.794 (1.499–2.296)
0.139
3.056 (2.488–4.031)
2.914 (2.371–3.532)
0.055
3.1515 (2.683–3.707)
2.973 (2.481–3.797)
0.348
1.917 (1.347–2.616)
2.015 (1.626–2.548)
0.420
2.877 (2.125–3.569)
2.630 (2.045–3.304)
0.004
1.974 (1.368–2.713)
2.239 (1.420–2.505)
0.735
3.120 (2.372–4.358)
2.809 (2.365–3.828)
0.003
EF
0.168 (0.149–0.187)
0.192 (0.134–0.251)
0.110
0.377 (0.282–0.460)
0.343 (0.236–0.425)
0.005
0.362 (0.290–0.432)
0.345 (0.252–0.423)
0.367
0.173 (0.139–0.198)
0.212 (0.171–0.291)
0.002
0.380 (0.306–0.475)
0.353 (0.277–0.428)
0.000
0.114 (0.063–0.174)
0.192 (0.142–0.336)
0.128
0.440 (0.324–0.499)
0.383 (0.275–0.462)
0.000
UF, UI, EF stated as median (upper quartile, lower quartiles), RP: Right parotid; LP: Left parotid; RS: Right submandibular; LS: Left submandibular; UF: Uptake fraction; UI: Uptake index; EF: Excretion fraction.
