Quantitative Scintigraphy Evaluated the Relationship between 131I Therapy and Salivary Glands Function in DTC Patients: A Retrospective Analysis

Table 4

Comparison of salivary gland function in patients before fourth treatment.

Scintigraphy parameters	Male group before fourth treatment number: 6					Female group before fourth treatment number: 8
	Before treatment	After first treatment	After second treatment	After third treatment		Before treatment	After first treatment	After second treatment	After third treatment
RP
UF	0.054 (0.024–0.072)	0.072 (0.035–0.089)	0.051 (0.025–0.077)	0.052 (0.015–0.076)	0.896	0.047 (0.043–0.056)	0.032 (0.031–0.046)	0.033 (0.018–0.037)	0.010 (0.009–0.042)	0.013
						VI-III 1.000 VI-II.231 VI-I .011 III-II 1.000 III-I .231 II-1 1.000
UI	2.237 (1.492–2.725）	2.3137 (1.691–3.522）	2.252 (1.425–3.257）	2.127 (1.323–2.668）	0.706	2.371 (1.860–2.885)	1.690 (1.537–2.151)	1.388 (0.808–1.844)	0.707 (0.529–1.887)	0.003
						VI-III 1.000 VI-II0.317 VI-I .003 III-II 1.000 III-I 0.040 II-1 0.728
EF	0.485 (0.330–0.559）	0.542 (0.460–0.705）	0.458 (0.364–0.547）	0.403 (0.004–0.548）	0.204	0.543 (0.500–0.567）	0.478 (0.439–0.487）	0.158 (0.023–0.446）	0.050 (0.022–0.407）	0.001
						VI-III 1.000 VI-II0.071 VI-I .006 III-II 0.199 III-I 0.022 II-1 1.000
LP
UF	0.040 (0.035–0.065）	0.052 (0.039–0.067)	0.041 (0.029–0.070)	0.031 (0.010–0.045)	0.849	0.041 (0.035–0.050）	0.035 (0.027–0.048)	0.033 (0.026–0.044)	0.025 (0.018–.035)	0.034
						VI-III 0.137 VI-II 0.231 VI-I 0.043 III-II 1.000 III-I 1.000 II-1 1.000
UI	1.958 (1.661–2.357)	2.3628 (1.468–2.616)	1.623 (1.307–3.080)	1.675 (1.213–1.995)	0.978	2.051 (1.765–2.396)	1.684 (1.534–2.175)	1.635 (0.963–2.104)	1.576 (0.472–2.029)	0.010
						VI-III 1.000 VI-II 1.000 VI-I .040 III-II 1.000 III-I 0.012 II-I0.317
EF	0.515 (0.480–0.589)	0.487 (0.385–0.575)	0.419 (0.216–0.548)	0.287 (0.047–0.48)	0.038	0.475 (0.454–0.526)	0.445 (0.297–0.485)	0.411 (0.031–0.501)	0.429 (0.016–0.518)	0.522
	I-III 1.000 VI-II 1.000 VI-I 0.044 III-II 1.000 III-1 0.152 II-1 1.000
RS
UF	0.053 (0.040–0.064)	0.057 (0.036–0.076)	0.050 (0.030–0.067)	0.040 (0.014–0.076)	0.284	0.052 (0.041–0.059)	0.039 (0.035–0.048)	0.043 (0.035–0.054)	0.037 (0.030–0.044)	0.021
						VI-III .043 VI-II .586 VI-I .043 III-II 1.000 III-I 1.000 II-1 1.000
UI	2.147 (1.884–2.778)	3.041 (2.015–3.985)	2.703 (1.927–3.185)	2.726 (1.660–4.742)	0.572	2.988 (2.479–3.495)	2.465 (2.125–3.067)	2.649 (2.306–2.857)	2.447 (2.239–2.601)	0.119
EF	0.386 (0.338–0.444)	0.352 (0.246–0.471)	0.394 (0.315–0.466)	0.422 (0.181–0.475)	0.940	0.437 (0.373–0.455)	0.282 (0.254–0.352)	0.284 (0.218–0.405)	0.348 (0.143–0.437)	0.010
						VI-III 1.000 VI-II 1.000 VI-I 0.317 III-II 1.000 III-I0.040 II-1 0.012
LS
UF	0.052 (0.044–0.056)	0.045 (0.043–0.078)	0.054 (0.041–0.063)	0.045 (0.015–0.070)	0.849	0.049 (0.042–0.056)	0.042 (0.030–0.047)	0.042 (0.034–0.049)	0.037 (0.030–0.040)	0.392
UI	2.605 (1.676–3.068)	3.420 (2.807–3.783)	3.023 (2.450–3.487)	2.904 (2.145–3.613)	0.706	2.550 (2.338–3.107)	2.620 (1.897–3.204)	2.666 (2.135–3.045)	2.472 (2.344–2.949)	0.789
EF	0.397 (0.350–0.456)	0.371 (0.255–0.427)	0.420 (0.297–0.504)	0.376 (0.166–0.453)	0.392	0.332 (0.269–0.407)	0.289 (0.259–0.355)	0.274 (0.194–0.405)	0.327 (0.129–0.415)	0.327

UF, UI, EF stated as median (upper quartile, lower quartiles). Examination before first, second, and third treatments expressed as I, II, III, and IV. The values were values after pairwise comparison of I, II, III, IV. RP: Right parotid; LP: Left parotid; RS: Right submandibular; LS: Left submandibular; UF: Uptake fraction; UI: Uptake index; EF: Excretion fraction.