Nomogram Models Based on the Gene Expression in Prediction of Breast Cancer Bone Metastasis

Figure 8

Receiver operating characteristic (ROC) analysis of the gene expression signature-based nomogram models in the training and validation cohorts. (a) ROC analysis of the predictive value of PR status, PES, stage, and four-gene risk score in the training cohort based on OS. (b) ROC analysis of the predictive value of PR status, PES, stage, and six-gene risk score in the training cohort based on PFS. (c) ROC analysis of the predictive value of PR status, PES, stage, and four-gene risk score in the GSE16446 as validation cohort based on OS. (d) ROC analysis of the predictive value of PR status, PES, stage, and six-gene risk score in the GSE16446 as validation cohort based on PFS. PR status, progesterone receptor status; PES, prior endocrine sensitivity; OS, overall survival; PFS, progression-free survival.

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