Nomogram Models Based on the Gene Expression in Prediction of Breast Cancer Bone Metastasis

Table 1

GO annotation and KEGG pathway analyses of differentially expressed genes.

Category	Term	Count	-value
GO annotation KEGG pathway	Signal transduction	170	9.70 E − 07
	Positive regulation of transcription from RNA polymerase II promoter	147	1.59 E − 06
	Immune response	84	2.93 E − 09
	Inflammatory response	81	2.00 E − 10
	Response to lipopolysaccharide	44	4.43 E − 09
	Extracellular exosome	421	5.95 E − 22
	Cytosol	442	1.98 E − 13
	Extracellular space	209	6.48 E − 12
	Cytoplasm	626	3.36 E − 10
	Membrane	294	6.25 E − 09
	Protein binding	1047	2.72 E − 14
	Poly(A) RNA binding	166	1.02 E − 06
	IgG binding	8	2.63 E − 05
	Double-stranded RNA binding	18	9.01 E − 05
	Identical protein binding	109	1.37 E − 04
KEGG pathway	Platelet activation	35	1.01 E − 05
	Phagosome	33	1.06 E − 03
	Proteoglycans in cancer	39	3.52 E − 03
	Lysosome	26	5.54 E − 03
	MAPK signaling pathway	46	5.81 E − 03
	Focal adhesion	39	5.88 E − 03
	Drug metabolism - other enzymes	13	7.84 E − 03
	Regulation of actin cytoskeleton	39	8.11 E − 03
	Leukocyte transendothelial migration	24	0.011
	Chemical carcinogenesis	18	0.015

Abbreviations. GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.