Research Article
Nomogram Models Based on the Gene Expression in Prediction of Breast Cancer Bone Metastasis
Table 1
GO annotation and KEGG pathway analyses of differentially expressed genes.
| Category | Term | Count | -value |
| GO annotation KEGG pathway | Signal transduction | 170 | 9.70 E − 07 | Positive regulation of transcription from RNA polymerase II promoter | 147 | 1.59 E − 06 | Immune response | 84 | 2.93 E − 09 | Inflammatory response | 81 | 2.00 E − 10 | Response to lipopolysaccharide | 44 | 4.43 E − 09 | Extracellular exosome | 421 | 5.95 E − 22 | Cytosol | 442 | 1.98 E − 13 | Extracellular space | 209 | 6.48 E − 12 | Cytoplasm | 626 | 3.36 E − 10 | Membrane | 294 | 6.25 E − 09 | Protein binding | 1047 | 2.72 E − 14 | Poly(A) RNA binding | 166 | 1.02 E − 06 | IgG binding | 8 | 2.63 E − 05 | Double-stranded RNA binding | 18 | 9.01 E − 05 | Identical protein binding | 109 | 1.37 E − 04 |
| KEGG pathway | Platelet activation | 35 | 1.01 E − 05 | Phagosome | 33 | 1.06 E − 03 | Proteoglycans in cancer | 39 | 3.52 E − 03 | Lysosome | 26 | 5.54 E − 03 | MAPK signaling pathway | 46 | 5.81 E − 03 | Focal adhesion | 39 | 5.88 E − 03 | Drug metabolism - other enzymes | 13 | 7.84 E − 03 | Regulation of actin cytoskeleton | 39 | 8.11 E − 03 | Leukocyte transendothelial migration | 24 | 0.011 | Chemical carcinogenesis | 18 | 0.015 |
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Abbreviations. GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.
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