The Pharmacological Mechanism of the Effect of Plant Extract Compound Drugs on Cancer Pain Based on Network Pharmacology

Table 13

Common targets of botanical drugs and cancer pain diseases.

141 common target proteins
ACHE	CD40LG	EGFR	HRH1	MAPK14	NR1I2	RAF1
ACTB	CES1	ERBB2	HSD3B2	MAPK8	NR3C1	RASA1
ADRA1A	CHEK2	ESR1	HSP90AA1	MDM2	NR3C2	RB1
ADRA2A	CHRM2	ESR2	HSPB1	MET	ODC1	RELA
ADRA2C	CHRM3	F3	HTR3A	MMP1	OPRD1	SCN5A
ADRB1	COMT	F7	ICAM1	MMP2	OPRM1	SELE
ADRB2	COX5A	FASLG	IFNG	MMP3	PCNA	SERPINE1
AKR1C1	COX6B1	FECH	IGF2	MMP9	PGR	SLC6A2
AKT1	CRP	FN1	IGFBP3	MPO	PIK3CG	SLC6A3
ALOX5	CXCL10	FOS	IKBKB	MT-CO1	PLAT	SLC6A4
AR	CXCL8	GABRA2	IL10	MTHFR	PLAU	SPP1
BAX	CYCS	GABRA3	IL1A	MTR	PON1	STAT1
BCL2	CYP19A1	GRIN1	IL1B	MYC	PPARA	THBD
BIRC5	CYP1A1	GRIN2A	IL2	NFE2L2	PPARG	TNF
CACNA2D1	CYP1A2	GRIN2B	IL4	NFKB1	PRKCA	TOP2A
CASP8	CYP27B1	GRIN2D	IL6	NFKBIA	PRSS1	TP53
CASP9	CYP2C9	GSTM1	IRF1	NOS2	PTGES	TYR
CAT	CYP3A4	GSTP1	JUN	NOS3	PTGS1	VCAM1
CAV1	DNMT1	HIF1A	KDR	NPPB	PTGS2	VDR
CCL2	EGF	HMOX1	MAPK1	NR0B1	PYGM	VEGFA
CCND1