Research Article
[Retracted] Clinical Potential of miR-451 and miR-506 as a Prognostic Biomarker in Patients with Breast Cancer
Table 1
Association of miR-451 and miR-506 with clinicopathological features of breast cancer patients.
| Parameters | N | miR-451 expression | miR-506 expression | Low (n = 49) | High (n = 39) | χ2 | | Low (n = 45) | High (n = 43) | χ2 | |
| Age, years | | | | 0.947 | 0.330 | | | 1.366 | 0.243 | ≤40 | 32 | 20 | 12 | | | 19 | 13 | | | >40 | 56 | 29 | 27 | | | 25 | 31 | | | Tumor size, cm | | | | 1.741 | 0.187 | | | 1.092 | 0.296 | ≤3 | 36 | 18 | 18 | | | 16 | 20 | | | >3 | 52 | 31 | 21 | | | 29 | 23 | | | LNM | | | | 4.503 | 0.034 | | | 6.527 | 0.011 | Negative | 43 | 19 | 24 | | | 19 | 24 | | | Positive | 45 | 30 | 15 | | | 28 | 17 | | | ER | | | | 3.215 | 0.073 | | | 1.31 | 0.252 | Negative | 34 | 23 | 11 | | | 20 | 14 | | | Positive | 54 | 26 | 28 | | | 24 | 30 | | | PR | | | | 1.108 | 0.292 | | | 0.682 | 0.409 | Negative | 33 | 16 | 17 | | | 15 | 18 | | | Positive | 55 | 33 | 22 | | | 30 | 25 | | | HER-2 | | | | 0.485 | 0.486 | | | 0.158 | 0.691 | Negative | 51 | 30 | 21 | | | 29 | 22 | | | Positive | 37 | 19 | 18 | | | 18 | 19 | | | TNM stage | | | | 4.946 | 0.026 | | | 4.632 | 0.031 | I-II | 47 | 21 | 26 | | | 19 | 28 | | | III-IV | 41 | 28 | 13 | | | 25 | 16 | | |
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LNM, lymph node metastasis; ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor receptor 2.
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